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Year Number of Results
1992 3
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2008 1
2012 1
2013 1
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2020 1
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Page 1
Interaction between protein kinase C and Exo1 (14-3-3 protein) and its relevance to exocytosis in permeabilized adrenal chromaffin cells.
Morgan A, Burgoyne RD. Morgan A, et al. Biochem J. 1992 Sep 15;286 ( Pt 3)(Pt 3):807-11. doi: 10.1042/bj2860807. Biochem J. 1992. PMID: 1417740 Free PMC article.
The observed synergy between PKC and Exo1 was not due to PKC-mediated phosphorylation of Exo1, and Exo1 was found not to affect PKC activity in enzyme assays. ...Furthermore, PKC does not directly affect Exo1, but rather enhances the activity of Exo
The observed synergy between PKC and Exo1 was not due to PKC-mediated phosphorylation of Exo1, and Exo1 was found not t …
Effect of a Ketogenic Diet on Oxidative Posttranslational Protein Modifications and Brain Homogenate Denaturation in the Kindling Model of Epilepsy in Mice.
Andreeva-Gateva P, Sabit Z, Bakalov D, Sayiner S, Tafradjiiska-Hadjiolova R, Zaharinova S, Abarova S, Koynova R, Tenchov B. Andreeva-Gateva P, et al. Neurochem Res. 2022 Jul;47(7):1943-1955. doi: 10.1007/s11064-022-03579-z. Epub 2022 Mar 22. Neurochem Res. 2022. PMID: 35316463
Two exothermic transitions (Exo1 and Exo2) were explored after deconvolution of the thermograms. ...The ratio of the two exothermic peaks (Exo2/Exo1) of the thermograms from the KD vs. SRC treated group differed more than twice (3.7 vs. 1.6). ...
Two exothermic transitions (Exo1 and Exo2) were explored after deconvolution of the thermograms. ...The ratio of the two exothermic p …
Exo1 and Exo2 proteins stimulate calcium-dependent exocytosis in permeabilized adrenal chromaffin cells.
Morgan A, Burgoyne RD. Morgan A, et al. Nature. 1992 Feb 27;355(6363):833-6. doi: 10.1038/355833a0. Nature. 1992. PMID: 1538762
Here we use this assay to identify two other cytosolic protein factors that regulate exocytosis in permeabilized adrenal chromaffin cells, which we term Exo1 and Exo2. Exo1 from brain cytosol resolves on electrophoresis in SDS-polyacrylamide gels as a group o …
Here we use this assay to identify two other cytosolic protein factors that regulate exocytosis in permeabilized adrenal chromaffin cells, w …
DNA repair genes in astrocytoma tumorigenesis, progression and therapy resistance.
Sousa JF, Serafim RB, Freitas LM, Fontana CR, Valente V. Sousa JF, et al. Genet Mol Biol. 2019 Dec 13;43(1 suppl 1):e20190066. doi: 10.1590/1678-4685-GMB-2019-0066. eCollection 2019. Genet Mol Biol. 2019. PMID: 31930277 Free PMC article.
Glioblastoma (GBM) is the most common and malignant type of primary brain tumor, showing rapid development and resistance to therapies. ...Excessive amounts of other DNA repair proteins, namely HJURP, EXO1, NEIL3, BRCA2, and BRIP, have also been connected to prolife …
Glioblastoma (GBM) is the most common and malignant type of primary brain tumor, showing rapid development and resistance to therapie …
Protein-protein networks analysis of differentially expressed genes unveils the key phenomenon of biological process with respect to reproduction in endangered catfish, C. Magur.
Kushwaha B, Srivastava N, Kumar MS, Kumar R. Kushwaha B, et al. Gene. 2023 Apr 15;860:147235. doi: 10.1016/j.gene.2023.147235. Epub 2023 Jan 30. Gene. 2023. PMID: 36731619
The present study was aimed at understanding the interaction of the brain-gonad system by analysing differentially expressed genes (DEG) in brains and gonads of male and female magur using a protein-protein network interaction study. ...Among them, cyp19a1b and amh …
The present study was aimed at understanding the interaction of the brain-gonad system by analysing differentially expressed genes (D …
Expression signatures of DNA repair genes correlate with survival prognosis of astrocytoma patients.
de Sousa JF, Torrieri R, Serafim RB, Di Cristofaro LF, Escanfella FD, Ribeiro R, Zanette DL, Paçó-Larson ML, da Silva WA Jr, Tirapelli DP, Neder L, Carlotti CG Jr, Valente V. de Sousa JF, et al. Tumour Biol. 2017 Apr;39(4):1010428317694552. doi: 10.1177/1010428317694552. Tumour Biol. 2017. PMID: 28378638 Free article.
Astrocytomas are the most common primary brain tumors. They are very resistant to therapies and usually progress rapidly to high-grade lesions. ...Moreover, silencing of EXO1, which is remarkably overexpressed, promoted faster restoration of double-strand breaks, wh …
Astrocytomas are the most common primary brain tumors. They are very resistant to therapies and usually progress rapidly to high-grad …
Polymorphisms of the DNA repair gene EXO1 modulate cognitive aging in old adults in a Taiwanese population.
Lin E, Kuo PH, Liu YL, Yang AC, Tsai SJ. Lin E, et al. DNA Repair (Amst). 2019 Jun;78:1-6. doi: 10.1016/j.dnarep.2019.03.013. Epub 2019 Mar 25. DNA Repair (Amst). 2019. PMID: 30928815
Our data showed that out of 1,652 SNPs, the rs1776181 (P = 1.47 10(-5)), rs1776177 (P = 8.42 10(-7)), rs1635510 (P = 7.97 10(-6)), and rs2526698 (P = 7.06 10(-6)) SNPs in the EXO1 gene were associated with cognitive aging. The association with these SNP remained significan …
Our data showed that out of 1,652 SNPs, the rs1776181 (P = 1.47 10(-5)), rs1776177 (P = 8.42 10(-7)), rs1635510 (P = 7.97 10(-6)), and rs252 …
Distinct disease-risk groups in pediatric supratentorial and posterior fossa ependymomas.
Godfraind C, Kaczmarska JM, Kocak M, Dalton J, Wright KD, Sanford RA, Boop FA, Gajjar A, Merchant TE, Ellison DW. Godfraind C, et al. Acta Neuropathol. 2012 Aug;124(2):247-57. doi: 10.1007/s00401-012-0981-9. Epub 2012 Apr 21. Acta Neuropathol. 2012. PMID: 22526017 Free PMC article.
Tumor cell density and mitotic count were associated with outcome among children with posterior fossa ependymomas (n = 119). Among pathologic features, only brain invasion was associated with outcome in children with supratentorial ependymomas (n = 27). ...In contrast, ris …
Tumor cell density and mitotic count were associated with outcome among children with posterior fossa ependymomas (n = 119). Among pathologi …
Whole-Exome Sequencing Reveals Migraine-Associated Novel Functional Variants in Arab Ancestry Females: A Pilot Study.
Khan J, Al Asoom L, Al Sunni A, Rafique N, Latif R, Alabdali M, Alhariri A, Aloqaily M, AbdulAzeez S, Jahan S, Banawas S, Borgio JF. Khan J, et al. Brain Sci. 2022 Oct 24;12(11):1429. doi: 10.3390/brainsci12111429. Brain Sci. 2022. PMID: 36358356 Free PMC article.
A total of 17 (p-value 9.091 10(-05)) functional variants in 12 genes (RETNLB, SCAI, ADH4, ESPL1, CPT2, FLG, PPP4R1, SERPINB5, ZNF66, ETAA1, EXO1 and CPA6) were associated with higher migraine risk, including a stop-gained frameshift (-13-14*SX) variant in the gene RETNLB …
A total of 17 (p-value 9.091 10(-05)) functional variants in 12 genes (RETNLB, SCAI, ADH4, ESPL1, CPT2, FLG, PPP4R1, SERPINB5, ZNF66, ETAA1, …
Exonuclease 1 is essential for maintaining genomic stability and the proliferative capacity of neural but not hematopoietic stem cells.
Zhang J, Yang R, Zhou D, Rudolph KL, Meng A, Ju Z. Zhang J, et al. Stem Cell Res. 2014 Jan;12(1):250-9. doi: 10.1016/j.scr.2013.11.001. Epub 2013 Nov 10. Stem Cell Res. 2014. PMID: 24280419 Free article.
Exonuclease 1 (Exo1) has been implicated in the regulation of DNA damage responses in stem cells with dysfunctional telomeres. ...In line with these results, we detected a decrease in proliferation and an up-regulation of p21 expression levels in Exo1-deficient NSCs …
Exonuclease 1 (Exo1) has been implicated in the regulation of DNA damage responses in stem cells with dysfunctional telomeres. ...In …
19 results